From Orlando to Miami
US Bus Station.com, Your Local Bus and Coach Route Database

You can take the bus to see the Zoo of Miami, one of the best of the Nation. Leave your car at home, and take a ticket to go to see the city we called "Little Cuba" or "Magic City".
Visit the Everglades with an air boat or enjoy a cruise from the Port of Miami, the number one cruise passenger port in the world!

Miami is located at 231miles in the South from Orlando.
A one way bus ticket cost 35$ approximately and the average duration of the ride is 4hours